在线客服

晓洁:

198-8659-7060

JEG-3人绒毛膜癌细胞[STR鉴定正确]

产品型号:BH-C068
产品规格:1×10^6cell/T25瓶
产品价格:¥1320

返回列表

商品详情相关试剂说明书下载参考文献

商品详情

目录号

BH-C068

细胞英文(简称)

JEG-3

细胞名称

JEG-3人绒毛膜癌细胞【已通过STR鉴定】

背景资料

这是一株超三倍体人类细胞株。 其典型染色体数为71,发生率为34%,多倍体率为2.6%t(4;11)(p15;q13), i(13q), t(10p15q), del(18)(q21),6个其他标记在大多数细胞中常见,另有两个标记在一些细胞中可见。 在一个N14和两个N22中可见大卫星。 N2, N5, N9 4个拷贝,而N7, N13, N18, N21 X为单拷贝。 Q-带检测法可以检测到单个Y染色体。

细胞来源

ATCC HTB-36

代次

P3

规格

冻存管/培养瓶

细胞数

1x10^6 cells

生物安全级别

1

组织来源

胎盘病变;绒毛膜癌

细胞形态

贴壁;上皮细胞样

细胞活力

95%(Viability by Trypan Blue Exclusion

细胞检测

细胞不含有HIV-1HBVHCV、支原体、细菌、酵母和真菌

培养条件

MEM+10%FBS(货号:C2056-1A+1%P/S37℃5% CO2

传代方法

建议1:2-1:3 两天换液一次

冻存条件

无血清细胞冻存液(货号:S002

参考文献

PubMed=5103722; DOI=10.1210/jcem-32-5-683
Kohler P.O., Bridson W.E.
Isolation of hormone-producing clonal lines of human choriocarcinoma.
J. Clin. Endocrinol. Metab. 32:683-687(1971)

PubMed=62839; DOI=10.1093/jnci/56.5.911
Lieblich J.M., Weintraub B.D., Krauth G.H., Kohler P.O., Rabson A.S., Rosen S.W.
Ectopic and eutopic secretion of chorionic gonadotropin and its subunits in vitro: comparison of clonal strains from carcinomas of lung and placenta.
J. Natl. Cancer Inst. 56:911-917(1976)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=7459858
Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=2878840; DOI=10.1016/0020-7292(86)90088-3
Yamashita K., Nakamura T., Shimizu T., Katagiri M., Ikeda H.
Expression of HLA class I and class II antigens in human choriocarcinoma cell lines.
Int. J. Gynecol. Obstet. 24:301-307(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=7937597; DOI=10.1016/0143-4004(94)90008-6
Grummer R., Hohn H.-P., Mareel M.M., Denker H.-W.
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15:411-429(1994)

PubMed=7753552
Brown A.D., Lopez-Terrada D., Denny C., Lee K.A.W.
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)

PubMed=7819056; DOI=10.1038/bjc.1995.3
Yaginuma Y., Yamashita T., Takuma N., Katayama H., Ishikawa M.
Analysis of the p53 gene in human choriocarcinoma cell lines.
Br. J. Cancer 71:9-12(1995)

DOI=10.1007/0-306-46861-1_8
Ganapathy V., Prasad P.D., Leibach F.H.
Choriocarcinoma.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.141-147; Kluwer Academic Publishers; New York (1999)

PubMed=11994546; DOI=10.1093/molehr/8.5.485
Blanchon L., Sauvant P., Bavik C., Gallot D., Charbonne F., Alexandre-Gouabau M.-C., Lemery D., Jacquetin B., Dastugue B., Ward S., Sapin V.
Human choriocarcinoma cell line JEG-3 produces and secretes active retinoids from retinol.
Mol. Hum. Reprod. 8:485-493(2002)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212
Li K.K.C., Goodall J., Goding C.R., Liao S.-K., Wang C.-H., Lin Y.-C., Hiraga H., Nojima T., Nagashima K., Schaefer K.-L., Lee K.A.W.
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=16797695; DOI=10.1016/j.placenta.2006.05.001
Burleigh D.W., Kendziorski C.M., Choi Y.J., Grindle K.M., Grendell R.L., Magness R.R., Golos T.G.
Microarray analysis of BeWo and JEG3 trophoblast cell lines: identification of differentially expressed transcripts.
Placenta 28:383-389(2007)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28161053; DOI=10.1016/j.placenta.2016.12.007
Abou-Kheir W., Barrak J., Hadadeh O., Daoud G.
HTR-8/SVneo cell line contains a mixed population of cells.
Placenta 50:1-7(2017)

PubMed=28724925; DOI=10.1038/s41598-017-06364-z
Rothbauer M., Patel N., Gondola H., Siwetz M., Huppertz B., Ertl P.
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892-5892(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Weber M., Weise A., Vasheghani F., Gohner C., Fitzgerald J.S., Liehr T., Markert U.R.
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)

联系我们
  • 19886597060