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G401人肾癌Wilms细胞[STR鉴定正确]

产品型号:BH-C348
产品规格:1x10^6cell / T25瓶
产品价格:¥1320

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商品详情相关试剂说明书下载参考文献

商品详情

目录号

BH-C348

细胞英文(简称)

G401

细胞名称

G401;人肾癌Wilms细胞

背景资料

该细胞来源于一名3个月大的婴儿的肾Wilms瘤,由于该类肿瘤分类的改变,经Garvin等鉴定后发现该细胞来源于肾横纹肌样瘤。该细胞分泌肾母细胞生长因子(nephroblast growth factorNB-GF)

细胞来源

ATCC

代次

P3

规格

冻存管/培养瓶

细胞数

1x10^6 cells

生物安全级别

2

组织来源

细胞形态

贴壁;上皮细胞样

细胞活力

95%(Viability by Trypan Blue Exclusion

细胞检测

细胞不含有HIV-1HBVHCV、支原体、细菌、酵母和真菌

培养条件

RPMI-1640+10% FBS(货号:C2056-1A+1% P/S 37℃,5% CO2

传代方法

建议1:2-1:3 两天换液一次

冻存条件

无血清细胞冻存液(货号:S002

参考文献

PubMed=8382007
Garvin A.J., Re G.G., Tarnowski B.I., Hazen-Martin D.J., Sens D.A.
The G401 cell line, utilized for studies of chromosomal changes in Wilms' tumor, is derived from a rhabdoid tumor of the kidney.
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Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.
Nature 394:203-206(1998)

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hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors.
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Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
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Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
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PubMed=28945250; DOI=10.1038/ng.3958
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PubMed=30924592; DOI=10.1002/pbc.27741
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WARNING: G-401 and SK-NEP-1 cell lines are not Wilms tumor cell lines.
Pediatr. Blood Cancer 66:e27741.1-e27741.2(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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Quantitative proteomics of the Cancer Cell Line Encyclopedia.
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PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
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